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Environment sufficient moisture is important factor for growing up microfungi, significant is relative moisture over 65 %. In dry area mushrooms are survived in location where remnants of moisture are often survived for longer time: leaves, clay, and condensation of water steam on windows and in the corner of rooms. Though microfungi need a high airiness of moisture to release spores into air, the microfungi need in certain development stage dry weather with flowing air. The microfungi also destroy foodstuffs, reserves of feeds and production of mycotoxin is not only depreciated them but endanger health of people and animals directly.Influence on human is very often and mostly directly proportional to concentration of fungi, theirs products and size of spores in the surrounding air. Target risk for human's health is to stay in rooms infested with fungi for long time.