The main objective of this paper is to investigate how different digitalisation measures have affected business performance in Czech companies during the pandemic. A questionnaire survey of Czech companies from various business sectors was used for data collection. The sample was defined randomly based on voluntary completion. For testing the hypotheses, the instruments used were one-factor ANOVA, Pearson Chi-square test. The study determines the digitalisation measures used and the change in the level of digitalisation of business processes. It provides an overview of the short-term impact of the measures on business performance. It confirmed the link between the growth in the level of digitalisation of external communication and the business sector (for industrial enterprises). Confirmed the association between the digitalisation of product offerings and service measures) and the level of digitalisation of marketing, the level of the website, the education and training of staff (measures), and the level of external communication. The association between the measures taken and the enterprise's financial situation during the pandemic was not confirmed. The results are limited to the Czech environment and the pandemic period. Due to how the sample is defined, insights regarding the wholesale and retail sectors are inconclusive. The study does not take into account long-term follow-up of changes.