The article considers third-order equations with multiple characteristics with general boundary value conditions and non-local initial data. A regular solution to the problem with known methods is constructed here. The uniqueness of the solution to the problem is proved by the method of energy integrals. This uses the theory of non-negative quadratic forms. The existence of a solution to the problem is proved by reducing the problem to Fredholm integral equations of the second kind. In this case, the method of Green’s function and potential is used.