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@article{55801, author = {Strunecká, Anna and Strunecký, Otakar}, article_location = {DUNEDIN}, article_number = {2}, keywords = {Aluminofluoride complexes; Autism spectrum disorders; Enzymes; Fluoride; G proteins; Neurotoxicity}, language = {eng}, issn = {2253-4083}, journal = {Fluoride}, title = {Paradoxes of fluoride toxicity}, url = {http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=4&SID=C5ABlKURYcXNXgIKdtV&page=1&doc=1}, volume = {53}, year = {2020} }
TY - JOUR ID - 55801 AU - Strunecká, Anna - Strunecký, Otakar PY - 2020 TI - Paradoxes of fluoride toxicity JF - Fluoride VL - 53 IS - 2 SP - 198-203 EP - 198-203 PB - International Society for Flouride Research SN - 22534083 KW - Aluminofluoride complexes KW - Autism spectrum disorders KW - Enzymes KW - Fluoride KW - G proteins KW - Neurotoxicity UR - http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=4&SID=C5ABlKURYcXNXgIKdtV&page=1&doc=1 L2 - http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=4&SID=C5ABlKURYcXNXgIKdtV&page=1&doc=1 N2 - Numerous literature sources reveal evidence that fluoride affects the activities of numerous enzymes in vitro as well as in vivo. Millions of people live in endemic fluoride areas with a severe public health problem. A plethora of data suggest that fluoride should be recognized as a developmental neurotoxicant for humans. The use of water fluoridation for the prevention of dental caries has increased the concern about adverse fluoride effects. The fluoride concentration at which a reduction in dental caries is expected is close to the level which might cause chronic pathological effects. We comment on how some of the conclusions of the recent review by Guth et al., published in Archives of Toxicology, are the emerging paradoxes in fluoride research. We show that fluoride has pluripotent effects, which might contribute to unexpected epidemics in the future. ER -
STRUNECKÁ, Anna and Otakar STRUNECKÝ. Paradoxes of fluoride toxicity. \textit{Fluoride}. DUNEDIN: International Society for Flouride Research, vol.~53, No~2, p.~198-203. ISSN~2253-4083. 2020.
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