The aim of the paper is to design the complex stock replenishment system to ensure production and distribution process continuity with efficient cost-spending. In order to achieve the predetermined objective, the stock replenishment concept was designed for individual stock groups created according to the stochasticity of their consumption. To compare the existing inventory management models, the added value of the proposed stock replenishment system consists in determining the appropriate order quantity, order cycle duration as well as ordering time. To specify the optimal order quantity, the proposed stock replenishment system regarding distribution uses the EOQ model as well as suggests a specific order quantity calculation for selected stock group. The comprehensive stock replenishment system applicable to a specific portfolio of industrial and distribution plant inventories is the most significant outcome of this research study.