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An indoor air quality seems to be one of the main problems of school buildings. This study evaluated the indoor air quality in Czech Republic by comparing the air change level and students performance in lecture halls. The parameters of interest were indoor carbon dioxide (CO2), total volatile organic compounds (TVOC), temperature, relative humidity (RH) and air change level. The difference in perceived air quality and odor intensity was obvious between the different ventilation conditions. The acceptability of air quality assessed by the sensory panels showed significant correlation with the values of CO2 and TVOC concentrations. The indoor air quality in Czech Republic classrooms affects the health of students. The school buildings relating to indoor European Standard are mostly evaluated as the non-low polluting buildings. Therefore, indoor air quality needs to be considered as an important problem concerning to study effectivity and students’ performance. The study of indoor air acceptability concerning to indoor odors under occupancy and its effect on perceived air quality influenced by air change rate are presented within the paper. The indoor air quality improving by higher ventilation levels 2, 4, 7 l/person, substantially improves the student’ performance (1 - 3 %). Increased ventilation rate usually will increase indoor air quality what definitely increase learning especially mathematic and problem tasks solving