On 1st May 2014 it was ten years since the Czech Republic accessed the European Union so that it is possible to assume the real impacts and benefits of our membership in the EU in the field of sustainable development of regions, which was a leitmotif for making up this monograph which follows the four previous succesful conference proceedings Sustainable Development in European Regions (2010), Sustainable Development in Economic Crisis (2011), Sustainable Development and Function of Modern European State (2012) and Aspects of Sustainable Development in programme Period 2007 - 2013 and Perspectives of Development in 2014 - 2020 (2013). The new monograph is a collection of various contributions and attitudes again and they try to outline the possibilities and solutions to sustainable development in the context of development of regions, municipalities and coutries. There are more then forty authors in the monograph, the professionals and scholars from the Czech Republic and abroad, Slovaia, Ukraine and Russia expecially. There are four many chapters in the monograph. Determinants of Competitiveness and Regional Development, Local Administration as a regional actor, Sustainable Development as a toll of regional development and development tolls of regions within which frames it focuses on individual aspects and selected problems of sustainable regional development. The book is primarily intended for scholars, empirical explorers and students but it can attact non-professionals dealing with the nature and current problems of sustainable development of regions as well.