Total joint replacement (TJR) is one of the most efficacious and cost effective procedures in surgery. It is applied to replace part of joint or all joint and must be secured the maintenance of absolute joint function. The functionality and lifetime of artificial joints in vivo are influenced by material properties, the shape of the implant, a combination of materials and also the reaction of the organism to a foreign object. The materials chosen must be biocompatible (both the material itself and any breakdown products), strong, resistant to fatigue, wear and corrosion, easily accessible and reasonably priced.