The article deals with the importance of e-learning within the process of adults’ education and further with its application in teaching of the subject "German language for economists" at the Institute of Technology and Business in České Budějovice. There are some definitions of e-learning in the introduction and some advantages and disadvantages of e-learning are described briefly. Then there is explained, how effectively can e-learning be used in connection with the Information System of the Institute. The article also deals with e-learning teaching methods in the seminar groups of the subject NEP_3 (German for Economists, 3rd semester). It focuses on the possibilities of using e-learning in the seminars of these groups and evaluates the efficiency and attractiveness of the e-learning instruments in the Information system of VŠTE. The results of a questionnaire conducted in three seminar groups NEP_3 showed that e-learning is an essential part of education at universities used commonly in the educational process.